Thermophilic cell factories for efficient conversion of brown algae biomass to high-value chemicals (ThermoFactories) | Marinebiotech

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Thermophilic cell factories for efficient conversion of brown algae biomass to high-value chemicals (ThermoFactories)

Abstract

Brown algae biomass is a promising and challenging resource for industrial bioconversions, but there is a need to develop efficient cell factories to convert the constituent carbohydrates into high-value added products. In this proposal, four metabolically different environmental bacteria, inherently suitable to harsh process conditions, will be engineered for production of a number of industrially important platform and specialty chemicals, including 1,2-propanediol, cadaverine, propanol and lycopene. The project will implement and integrate systems biology and metabolic engineering, including rounds of model-driven metabolic optimization. Feedstock development and process engineering are important parts, to optimize fermentability of the algal hydrolysates, and ensure integration with downstream processing and product recovery. At the end of the project, use of all major carbohydrate fractions from brown algae through integrated processing will be demonstrated at small pilot scale.

Coordinator

Dr Trygve Brautaset, Norwegian University of Science and Technology, Norway

Consortium

Name

Organisation

Country

Trygve Brautaset

Norwegian University of Science and Technology

Norway

Alexander Wentzel

SINTEF Materials and Chemistry

Norway

Steinn Gudmundsson

University of Iceland

Iceland

Eva Nordberg Karlsson

Lund University

Sweden

Jochen Förster

Technical University of Denmark

Denmark

Gudmundur Oli Hreggvidsson

Matis Ohf

Iceland

Bruno Ferreira

Biotrend SA

Portugal

Simão Soares

SilicoLife Lda

Portugal

Factsheet

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